Self-employment is an option you may be keen to explore. You may have an idea for a business that you want to pursue and that will use your particular skills. You may want to work from home if this is well set up to accommodate your needs. Being self-employed may allow you more flexibility with the hours you work and the development of IT has made this option more and more possible. There are rules about things like tax and national insurance contributions so careful research will help you plan.
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For information on self-employment in England, Scotland and Wales: www.gov.uk/browse/business
In England, Scotland and Wales, JobCentre Plus can provide you with information about setting up your own business. You might be able to get financial assistance from Access to Work: www.gov.uk/access-to-work and New Enterprise Allowance: www.gov.uk/government/collections/new-enterprise-allowance-campaign